Thermolabiele, flexibele endoscopen Module 2c Risk-of-bias-tabel

Author, year

Selection of participants

Was selection of exposed and non-exposed cohorts drawn from the same population?

Exposure

Can we be confident in the assessment of exposure?

Outcome of interest

Can we be confident that the outcome of interest was not present at start of study?

Confounding-assessment

Can we be confident in the assessment of confounding factors? 

Confounding-analysis

Did the study match exposed and unexposed for all variables that are associated with the outcome of interest or did the statistical analysis adjust for these confounding variables?

Assessment of outcome

Can we be confident in the assessment of outcome?

Follow up

Was the follow up of cohorts adequate? In particular, was outcome data complete or imputed?

Co-interventions

Were co-interventions similar between groups?

Overall Risk of bias

Definitely yes, probably yes, probably no, definitely no

Definitely yes, probably yes, probably no, definitely no

Definitely yes, probably yes, probably no, definitely no

Definitely yes, probably yes, probably no, definitely no

Definitely yes, probably yes, probably no, definitely no

Definitely yes, probably yes, probably no, definitely no

Definitely yes, probably yes, probably no, definitely no

Definitely yes, probably yes, probably no, definitely no

Low, Some concerns, High

Eichel, 2021

Definitely yes

Reason: Identical test tubes were used that were contaminated using the same method

Probably yes

Reason: Exposure was introduced in all samples using the same method.

Definitely yes

Reason: Outcome is reduction of the introduced contamination.

Probably no

Reason: No positive or negative controls were used.

Not applicable

Definitely no

Reason: Limited repetitions for all timepoints except 16 hours.

Not applicable

Not applicable

Some concerns (other outcomes)